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IVF & ART

ETZ Tilburg: thirty minutes of margin, and no more

New benchtop incubators cool down far faster than the boxes they replaced. The reaction window shrank, so the watch had to tighten with it.

Monitoring since
Over 20 years
Overhaul
2022
Reaction window
30 minutes
Embryologists at work in the ETZ IVF laboratory in Tilburg

The change

In 2022 the ETZ IVF laboratory replaced its water jacketed box incubators with Esco Miri benchtop incubators. At the same time the XiltriX system, already in use for almost two decades, was overhauled to match the new equipment.

Water jacketed incubators hold their temperature for hours. Benchtop chambers do not. The physics changed, and with it the amount of time anyone has to respond.

What that means in practice

Measurement frequency matters more than alarm volume. Updates arrive multiple times per minute, so a drift is visible while it is still a drift, and staff can be on their way before it becomes damage.

Two decades of history in the same system also gave the team a baseline. When a new chamber behaves differently from the rest, it shows up against years of recorded normal.

"In the new benchtop incubators we only have 30 minutes or less to get to the lab before embryos incur viability damage. Having XiltriX, which provides measurement updates multiple times per minute, allows for a rapid response."

Dr Dimitri Consten, Laboratory director, ETZ IVF Tilburg